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ccg-100602 1-[3,5-bis (trifluoromethyl)benzoyl]- n -(4-chlorophenyl)-3-piperidinecarboxamide  (Cayman Chemical)

 
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    Structured Review

    Cayman Chemical ccg-100602 1-[3,5-bis (trifluoromethyl)benzoyl]- n -(4-chlorophenyl)-3-piperidinecarboxamide
    Ccg 100602 1 [3,5 Bis (Trifluoromethyl)Benzoyl] N (4 Chlorophenyl) 3 Piperidinecarboxamide, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ccg-100602 1-[3,5-bis (trifluoromethyl)benzoyl]- n -(4-chlorophenyl)-3-piperidinecarboxamide/product/Cayman Chemical
    Average 90 stars, based on 1 article reviews
    ccg-100602 1-[3,5-bis (trifluoromethyl)benzoyl]- n -(4-chlorophenyl)-3-piperidinecarboxamide - by Bioz Stars, 2026-02
    90/100 stars

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    Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor <t>CCG-100602</t> or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05
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    Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor <t>CCG-100602</t> or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05
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    Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor <t>CCG-100602</t> or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05
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    https://www.bioz.com/result/ccg-100602 1-[3,5-bis (trifluoromethyl)benzoyl]- n -(4-chlorophenyl)-3-piperidinecarboxamide/product/Cayman Chemical
    Average 90 stars, based on 1 article reviews
    ccg-100602 1-[3,5-bis (trifluoromethyl)benzoyl]- n -(4-chlorophenyl)-3-piperidinecarboxamide - by Bioz Stars, 2026-02
    90/100 stars
      Buy from Supplier

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    Cayman Chemical ccg-100602
    Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor <t>CCG-100602</t> or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05
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    ApexBio ccg-100602
    Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor <t>CCG-100602</t> or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05
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    Image Search Results


    Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor CCG-100602 or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05

    Journal: Stem Cell Research & Therapy

    Article Title: Activin B-activated Cdc42 signaling plays a key role in regulating adipose-derived mesenchymal stem cells-mediated skin wound healing

    doi: 10.1186/s13287-022-02918-9

    Figure Lengend Snippet: Activin B-induced ADSCs proliferation by activating Cdc42-Erk-Srf pathway. A Genes expression related to MAPK signaling in Act B+ADSCs (Cdc42N17) group. B qPCR analysis was performed to confirm the relative mRNA expression level of Srf in four groups. C , E Western blot assays were performed to detect the level of Srf and phosphorylation Erk (p-Erk) in ADSCs, activin B+ADSCs, ADSCs (SCH772984) (Erk1/2 inhibitor) or ADSCs (Cdc42N17) treated with or without activin B, respectively. D , F The band and the relative quantification levels of the expression of Srf and phosphorylation Erk were analyzed. G Representative fluorescence imaging of EdU staining of ADSCs and ADSCs treated with Srf inhibitor CCG-100602 or Erk1/2 inhibitor SCH772984 and with/without activin B at 6 h. Scale bar = 50 μm. H The proliferation rates were quantified by calculating the percentage of EdU-positive cells. All values are expressed as mean ± SD from three independent repeats. * P < 0.05

    Article Snippet: Cells were serum-starved for 12 h and then treated with serum-free H-DMEM containing Srf inhibitor CCG-100602 (15 μM, Cat# HY-120855, Mce) for 24 h [ , ] or Erk1/2 inhibitor SCH772984 (5 μM, Cat# S7101, Selleck) for 2 h [ ].

    Techniques: Expressing, Western Blot, Fluorescence, Imaging, Staining